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They may include: Peripheral neuropathy can also affect your bodys automatic functions

doi: 10.1016/S2213-8587(19)30066-X 32 CapehornMSCatarigA-MFurbergJKJanezAPriceHCTadayonSet al

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First, it acted as a competitive inhibitor of 2-oxoglutarate-dependent dioxygenase (2-OGDD) function, and secondly, glutarate accumulation impaired activity of the pyruvate dehydrogenase complex (PDHc)