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Meanwhile, oxidative stress from excess copper depletes glutathione, catalase, and superoxide dismutase the same antioxidants that protect mitochondria and neurons

101,102 ME2 depletion, accompanied by an increased NADP + /NADPH ratio and ROS levels, impacts PI3K/AKT signaling and enhances the sensitivity of erythroleukemia and NSCLC cells to cisplatin

In tumors, low concentrations ROS may function as signaling molecules favoring tumorigenesis and heterogeneity [106]

GLP-1 receptor agonists like Ozempic and Wegovy have

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